Universitäts-Kinderspital Zürich
Head of Mass Spectrometry 80 - 100 %
Start of employment As soon as possible, temporaryNCCR Children & Cancer
Your responsibilities
- You will lead the day-to-day operations of the MS platform, including scheduling, quality control and sample throughput across metabolomics, isotope tracing and other MS-omics workflows.
- In this role, you drive method development for LC-MS/MS-based stable isotope tracing, metabolomics, RNA modifications and lipid analysis, including applications to in vivo and patient-derived samples.
- You ensure high data quality, robust data management and fully reproducible workflows through rigorous QC and precise documentation.
- You will co-develop and implement automated sample preparation workflows to increase throughput and improve reproducibility.
- Co-design of the data acquisition and processing infrastructure around Orbitrap Astral instruments will be part of your responsibilities.
- You maintain mass spectrometry instruments at the highest performance standards and manage service contracts as well as consumables.
- Contribution to the development of single-cell mass spectrometry methods is expected as part of the lab's technology development agenda.
- You actively contribute to research projects, from experimental planning and data interpretation through to manuscript writing.
- Training and mentoring of graduate students, postdocs, and collaborators in MS techniques and experimental design is an important part of your work.
- You advise on and support the procurement of future equipment and contribute to grant applications for infrastructure funding.
- You represent the platform in internal and external collaborations across the Zurich life sciences community.
Your profile
- Expert (MSc or PhD) in analytical chemistry, biochemistry, or a closely related field - with a strong mass spectrometry track record; Experience matters
- Hands-on expertise with high-resolution LC-MS platforms, ideally including Orbitrap-based instruments
- Proven experience in stable isotope tracing and/or metabolomics in a biological research context - this is central to the lab's work
- Demonstrated ability to develop and optimize analytical methods from first principles
- Interest in or experience with single-cell mass spectrometry technologies is a plus
- Experience mentoring or teaching MS techniques to non-specialists
- Strong publication record showing independent scientific contributions
- Experience running or co-running a core or research facility is a strong plus, not prerequisite
- Fluent in English; German is an asset but not required
What we offer
Our employees benefit from a wide range of attractive offers. Find out more: https://www.uzh.ch/de/explore/work.html.
What we offer
Further information
Questions about the job
Dr. Dr. med. univ. (A) Raphael Morscher Research Group Leader +41 44 249 65 84
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Questions about the application procedure
Yigit Baskan HR Business Partner +41 44 249 23 03
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Working at UZH
The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields. With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education. Put your talent and skills to work with us. Find out more about UZH as an employer!
More → https://www.uzh.ch/en/explore/work.html
The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields. With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education. Put your talent and skills to work with us. Find out more about UZH as an employer!
More → https://www.uzh.ch/en/explore/work.html
Working at UZH
The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields. With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education. Put your talent and skills to work with us. Find out more about UZH as an employer!
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