Staff Mass Spectrometrist (m/f) 100%

NCCR Children & Cancer

The Morscher Laboratory works at the intersection of pediatric oncology and fundamental research in metabolism. Stable isotope tracing is a core methodology of the lab - applied across cell culture, animal models, and directly in patients to map metabolic fluxes at quantitative resolution. We combine this with single-cell metabolomics, RNA mass spectrometry, and proteomics to decode metabolic programs from the whole organism down to the single cell - and to translate these insights into new treatment strategies for children with cancer.
Your responsibilities
  • You operate and maintain the mass spectrometry infrastructure, including Orbitrap Astral instruments and supporting LC systems, ensuring consistently high performance.
  • Coordination, preparation, and processing of biological samples for stable isotope tracing, metabolomics, epitranscriptomics, and other MS-omics analyses - including low-input and single-cell samples - are part of your responsibilities.
  • You support the implementation of automated sample preparation pipelines to increase throughput and improve reproducibility.
  • Hands-on guidance and training of students and postdocs in the use of the instruments is an important part of your role.
  • You actively contribute to the development and optimization of LC-MS methods for metabolite quantification, isotope enrichment, lipid profiling, and modified nucleotides.
  • Routine instrument calibration, troubleshooting, and preventive maintenance are carried out by you independently.
  • You support data acquisition as well as initial QC and processing pipelines.
  • You perform MS data processing and analysis across applications and collaborative projects, ensuring high data quality and consistency.
  • You manage MS data across projects to ensure traceability, organization, and reproducibility.
  • You also help manage consumables, sample logistics, and platform documentation.
Your profile
  • Expert (MSc or PhD) in analytical chemistry, biochemistry, or a related field
  • Solid practical experience with LC-MS/MS - ideally on Orbitrap-based instruments
  • Background in stable isotope tracing and/or metabolomics in a biological setting is strongly preferred
  • Interest in or experience with laboratory automation - liquid handling, automated sample prep, or scripted workflows
  • Curiosity about emerging technologies, particularly single-cell mass spectrometry, is a genuine plus
  • Methodical, detail-oriented, and comfortable troubleshooting complex instrument issues
  • Able to work independently and communicate clearly with researchers at all levels
  • Experience in a core facility, CRO, or research lab environment is valued
  • English required; German is a plus

Your salary

The exact salary will depend on your qualifications and professional experience. Your salary will be established in accordance with our salary guidelines during the selection process.

show moreShow less

Contact

Dr. Dr. med. univ. (A) Raphael Morscher
Research Group Leader
+41 44 249 65 84

Onkologie
Yigit Baskan
HR Business Partner
+41 44 249 23 03 Apply now
Your start with us
We can offer you the position as early as possible.

The application process

After you have submitted your application via our online portal, we will consider it carefully. We will make an initial selection from among the applications received and then get in touch with you. If we progress to the interview stage, the following procedure will apply:

application process

Your benefits

Leave the car at home.

All employees with at least 50% employment level and a contract duration of 6 months or longer benefit from CHF 500 discount per year on the SBB GA travel card or get at least 25% discount on the ZVV BonusPass for the entire ZVV network.

Mix your own smoothies.

Enjoy the healthy and tasty menu of the day in our staff restaurant for just CHF 9.00. With a varied salad buffet, juice bar, muesli bar and cake buffet, the restaurant caters for every taste.

Have you heard about the "Frauenbadi"?

Don’t worry – there’s a men’s one too! Located in the heart of Europe and right next to a lake, Zurich strikes the perfect balance between modern city life and stunning nature. Zurich is the education and economic centre of Switzerland and hosts countless events and a wide range of activities – there’s some-thing for everyone! More information about working in Switzerland can be found here.

We love all children - including yours!

We have signed a contract with the GFZ foundation day care centre, located near the Kispi, meaning you can benefit from longer day care at the same price. Your children can stay at the day care centre from 6:30 am to 6:30 pm.​

show more

We will help you through difficult times.

With an employment level of at least 20%, you will enjoy worldwide private insurance coverage in the event of an accident at work or in your free time. Even below 20%, you benefit from private occupational accident insurance with additional general coverage for non-occupational accidents.

Take a city break!

Every five years, you’ll be rewarded for your loyalty with extra holiday days. Previous roles at the Children’s Hospital will be counted.

Get well soon!

Have you worked for us for more than three months in at least a 0.2 FTE position? In most cases, you will benefit from Helsana daily sickness benefits insurance. In the event of illness, you will receive a daily allowance amounting to 80% of your salary for up to 720 days.

Head to the south!

If your five weeks of holiday aren’t enough, we’ll do our best to let you take unpaid holiday.

We fill your piggy bank

We assume 60% of your pension fund contributions, which exceeds the statutory minimum. As a part-time employee, you also benefit from a reduced coordination offset.

Spend more time with your children.

With interesting part-time roles available, we aim to give our employees the opportunity to balance their career with family life. For example, if you’ve just started a family or are finishing up a degree, you can look into reducing your working hours at the Children’s Hospital.

We'll update your vaccination record.

The staff doctor isn’t just there for emergencies – you can consult them about vaccinations and occupational health.

Let’s write history.

We work in the modern new building of the University Children’s Hospital Zurich in the Lengg district. The building combines pioneering architecture with state-of-the-art infrastructure and smooth work processes. Spacious rooms, innovative medical technology and a well-designed environment create the best conditions for our patients and everyone who works here. Help us shape the future of paediatric medicine.

Surpass yourself.

No matter what stage of your career you are at, the Children’s Hospital Zurich can help you go further. Our career models for nurses, doctors and in research offer you a huge variety of development opportunities for your specialist or management career.

Treat yourself.

We are a member of Corporate Benefits, the benefits portal for employees. This gives you attractive discounts and special conditions on many well-known brands from the worlds of fashion, technology, travel and leisure.

Kinderspital Zürich as an employer
Kinderspital Zürich is the largest university children's hospital in Switzerland with about 2,500 employees, and is one of the leading centres for paediatric and youth medicine in Europe. Although the hospital may be big, it's the little ones that count: up to 100,000 patients are cared for each year across 47 faculties, where we do everything in our power to ensure their well being. 'Kispi' not only offers cutting-edge devices and the highest quality of care, but also a good sense of interpersonal issues. Alongside its comprehensive range of paediatric medicine and surgery facilities, the children's hospital also offers a unique rehabilitation centre and a research centre.

Your location

Lenggstrasse 30
8008 Zürich
Open Google Maps